
- Posted by Nick Brown
At the onset of the season, the Buffalo Bills are the hottest brand in the betting on NFL future market. Buffalo is the public choice to win the Super Bowl. Something they could have done in 2021. If not for leaving Patrick Mahomes and the Kansas City Chiefs 16 seconds to rise from death. But the Bills vow they have fully recovered from heartbreak in KC. Meanwhile, the Rams are defending Super Bowl champions. But their path was precarious and could have been derailed several times. LA’s high wire act showed how delicate a championship path is.
NFL Betting: Buffalo Bills vs. Los Angeles Rams Information
Date: | Thursday, September 8, 2022 |
Time: | 8:20 p.m. ET |
Location: | SoFi Stadium, Inglewood, California |
TV Coverage: | NBC |
Buffalo Bills vs. Los Angeles Rams Betting Odds
Team | SP/RL | TOTAL | ML | |
---|---|---|---|---|
Bills | -2½ ( -110 ) | 52 ( -110 ) | -135 | Place Bets |
Rams | +2½ ( -110 ) | 52 ( -110 ) | +115 | |
Place Bets |
Buffalo Bills vs. Los Angeles Rams CashBet Wagering Analysis
Indeed, the new season kicks off with a bang in the NBC 2022 NFL Kickoff Game on Thursday. The LA Rams are the reigning Super Bowl champions. At the same time, the Bills are the 2023 online sportsbook Super Bowl favorites.
Both teams have high-powered offenses. Namely, Josh Allen is at QB for the Bills, and Matthew Stafford is leading the Rams. Also, Buffalo had the league’s best defense in 2021. In comparison, LA’s pass rush led by Aaron Darnold gives opponents fits. Last time these teams met was in 2020 at Buffalo. The Bills scored on an Allen touchdown pass with 15 seconds left to take a 35-32 victory. NBC, fans, gamblers, and sportsbooks can’t ask for more in an opener.
Gamblers Expect Buffalo to Pay the Bills in 2022
Overall, Buffalo rates as one of the league’s most balanced teams. Last year the Bills allowed just 278 total yards and 17 points per game. First in the NFL was their ranking in each of those categories. The Rams ranked 17th in total yards and 15th in points. Thus, Allen and receiver Stefon Diggs should be able to exploit a Rams secondary that finished 22nd in allowing 242 passing yards per game. Also, LA’s star corner Jalen Ramsey might not be 100%.
Last season Allen threw for 4,407 yards and 36 TDs. He was sacked just 26 times. Second-fewest in the league behind Tom Brady. Cause by his ability to make plays with his legs. Allen rushed for 763 yards, 25th-most in the NFL. When Allen throws, he often looks for big plays from Diggs. To summarize, Diggs had 103 catches for 1,225 yards and 10 TDs in 2021.
Buffalo’s secondary is tough to crack. And LA QB Matthew Stafford shared the NFL lead with 17 interceptions last season.
Rams Repeat No Sure thing
The Los Angeles passing offense is unquestionably one of the most dangerous in Betting on football. Last season Stafford threw for 4,886 yards. And his 41 TD passes ranked second in the NFL. Cooper Kupp was a major part of the success. To show, Kupp scored 16 of those TDs in his stellar season. His 145 receptions and 1,947 yards are both second-best in NFL history.
Meanwhile, Cam Akers rushed for 625 yards as an NFL bets rookie. And he showed burst while posting 248 total yards in four postseason games. Darrell Henderson added 4.6 yards per rush in 2021. And he can carry the load if necessary. Aaron Donald is the lynchpin of the Rams’ defense. The three-time Defensive Player of the Year led a unit ranked third in the NFL with 50 sacks. In sum, Donald had 12.5 sacks and forced four fumbles. The Rams had 25 takeaways in 2021.
Bills vs. Rams CashBet Free Pick
Overall, the Bills are 13-6-2 against the NFL Betting odds in non-conference games under coach Sean McDermott. Buffalo is 4-1 against the spread in the past five meetings between these teams. Also, the Bills went 3-2 ATS as a road favorite last season. Since Sean McVay became coach, Los Angeles is 5-0 ATS in its five Week one games, winning each tilt straight-up. On this occasion, defending champion Los Angeles makes for an appealing value as a home dog.
Bills vs. Rams CashBet Best Bet
Los Angeles Rams

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