2022 NFL Week Two Preview, Betting Analysis and Predictions

Since 1960 the Los Angeles Chargers and Kansas City Chiefs have shared the same AFC West Division.  This year the Chargers are seen as a serious Super Bowl best threat to end the Chiefs AFC West dynasty.  Kansas City will host the Chargers to kick off week two action at Arrowhead Stadium on Thursday, September 15.  Specifically, Prime Video will provide coverage with its new team of Al Michaels and Kirk Herbstreit.  This matchup features two of the hottest quarterbacks in the NFL.  Justin Herbert of the Chargers and Patrick Mahomes of the Chiefs bring star power.

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2022 NFL Week Two Schedule – All Times Eastern 

Thursday, September 15, 2022

Los Angeles Chargers at Kansas City Chiefs – 8:15 PM – Prime Video

Sunday, September 18, 2022

New York Jets at Cleveland Browns – 1 PM – CBS
Washington Commanders at Detroit Lions – 1 PM – FOX

Tampa Bay Buccaneers at New Orleans Saints – 1 PM – FOX

Carolina Panthers at New York Giants – 1 PM – FOX
New England Patriots at Pittsburgh Steelers – 1 PM – CBS

Indianapolis Colts at Jacksonville Jaguars – 1 PM – CBS
Miami Dolphins at Baltimore Ravens – 1 PM – CBS

Atlanta Falcons at Los Angeles Rams – 4:05 PM – FOX

Seattle Seahawks at San Francisco 49ers – 4:05 PM – FOX

Cincinnati Bengals at Dallas Cowboys – 4:25 PM – CBS

Houston Texans at Denver Broncos – 4:25 – CBS

Arizona Cardinals at Las Vegas Raiders – 4:25 PM – CBS

Chicago Bears at Green Bay Packers – 8:20 PM – NBC

Monday, September 19 

Tennessee Titans at Buffalo Bills – 7:15 PM – ESPN

Minnesota Vikings at Philadelphia Eagles – 8:30 PM – ABC

Steelers Host Patriots in Key AFC Matchup

Last year the New England Patriots rode rookie quarterback Mac Jones to an unexpected AFC playoff berth.  In like manner, the Pittsburgh Steelers could do that same with rookie Kenny Pickett.  Pittsburgh will host the Patriots in a key best sportsbook online matchup that could have strong AFC playoff implications.

NFL’s Oldest Rivalry Renews on NBC Sunday Night Football

The Green Bay Packers are a perennial betting on Super Bowl favorite and will host their ancient rival Chicago Bears on NBC Sunday Night Football.  Green Bay quarterback Aaron Rodgers has lost his top receiver, Davante Adams.  Of great concern to gamblers is how he will adjust.  Meanwhile, the Bears will be playing for new head coach Matt Eberflus.  The Bears will be trying to get second year quarterback Justin Fields up to speed.  But can they give Fields a good supporting cast?

Monday Night Football Doubleheader  

On Monday, September 19, week two will end with a Monday Night Football doubleheader.  The Buffalo Bills will host the Tennessee Titans in a matchup of AFC playoff contenders.  Buffalo is among the top favorites with the Super Bowl betting odds.  This ESPN matchup should have major AFC playoff implications.   Tennessee may have a quarterback controversy on its hands for this game.  Ryan Tannehill is coming off a bad season and will be challenged by rookie Malik Willis.

And then, 85 minutes later, the Philadelphia Eagles will host the Minnesota Vikings on ABC.  These two NFC teams are Wannabe contenders that lack Super Bowl betting credibility.  It is true that the Eagles made the 2021 NFL playoffs.  But only because of the expanded format.  Philadelphia quarterback Jalen Hurts continues to face the doubts of the football community.  In like manner, Vikings quarterback Kirk Cousins has squandered almost all of his credibility.