
- Posted by Nick Brown
One of the great old NFL rivalries will be renewed on Monday night. To show, the Rams and 49ers go back to the 1950s with some of the greatest battles in NFL history. This year Los Angeles has the upper hand as a Super Bowl best bet. Specifically, the arrival of quarterback Matthew Stafford in at trade has catapulted the Rams as top-tier favorites. San Francisco has never been the same since taking their presumptive Super Bowl championship photo before an epic loss minutes later. Injuries are a constant companion of the 49ers. This albatross is yet to be shaken.
Los Angeles Rams vs. San Francisco 49ers Betting Information
Date: | Monday, November 15, 2021 |
Time: | 8:15 pm ET |
Location: | Levi’s Stadium, Santa Clara, California |
TV Coverage: | ESPN |
Rams vs. 49ers Betting Odds
Team | SP/RL | TOTAL | ML | |
---|---|---|---|---|
Rams | -4 ( -110 ) | 49 ( -110 ) | -200 | Place Bets |
49ers | +4 ( -110 ) | 49 ( -110 ) | +170 | |
Place Bets |
Los Angeles Rams at San Francisco 49ers CashBet Wagering Analysis
Certainly, the top online sportsbook betting public will prefer the Rams. Los Angeles is a new team with Matthew Stafford at quarterback. San Francisco has lost credibility with a public that is tired of being burned by the 49ers. Thus, Wise Guys may see San Francisco as a contrarian bet.
Los Angeles Rams Through NFC West
Last week the Rams lost to Tennessee 28-16 as 7-point home favorites. The Rams and Titans game went under the Betting on Super Bowl total of 53. As a result, Los Angeles is 7-2 straight up, 4-5 against the spread, and 5-3-1 over/under. Overall, LA ranks 4th for total offense and 5th for scoring offense. Defensively, the Rams rank 12th overall and 11th for points allowed.
Kevin Byard returned Matthew Stafford’s second consecutive interception 24 yards for a touchdown. On the whole, Tennessee’s defense carried the night in an impressive upset. QB Ryan Tannehill passed for 143 yards and a touchdown. Also, he rushed for another score for the Titans. Tennessee managed just 194 offensive yards in their first game without injured NFL rushing leader Derrick Henry.
Adrian Peterson rushed for just 21 yards. But the veteran running back made a 6-yard TD run with 3:00 left in the first game of his 15th NFL season.
Fools Gold in San Francisco Tarnishes Brand
Last week San Francisco lost at home to Arizona 31-17 as 5.5-point home dogs. The game went over the Super Bowl betting odds total of 45. As a result, the 49ers are 3-5 straight up, 2-6 against the spread, and 5-3 over/under. Overall, San Francisco ranks 13th for total offense and 18th for scoring offense. Defensively, the 49ers rank 8th overall and 25th for points allowed.
Of major concern is that the 49ers could not take advantage of an Arizona team decimated by injuries. Including QB Kyler Murray and receivers DeAndre Hopkins and AJ Green.
Los Angeles Rams at San Francisco 49ers Against the Spread
On the road, Los Angeles is 59% against the spread. While as a favorite, the Rams are 58% vs. the odds. In division games, the Rams are 64% against the spread. As an away team, Los Angeles is 57% over the total. Overall, as a favorite, the Rams are 71% under the total. And in division games, Los Angeles is 60% under the total.
At home, San Francisco is 38% against the spread. While as an underdog, the 49ers are 67% vs. the odds. In division games, the 49ers are 46% against the spread. As a home team, San Francisco is 57% over the total. Overall, as an underdog, the 49ers are 67% under the total. And in division games, San Francisco is 53% under the total.
Los Angeles is 3-8 against the spread vs. the 49ers. The Rams and 49ers are 2-4 over/under the total. Specifically, at San Francisco, Los Angeles is 2-1 vs. the odds against the 49ers. Further, these two teams are 2-4 over/under the Super Bowl betting total at San Francisco.
Los Angeles Rams at San Francisco 49ers CashBet Free Pick
As mentioned earlier, the Rams have shown good NFL gambling value at San Francisco, on the road, and against the NFC West. Counter to that is San Francisco’s poor value at home.
Rams at 49ers CashBet Best Bet:
Los Angeles Rams

Promotions
HeadLines
-
NFL Football
/ 2 years agoAnother Giant Leap Forward Expected for New York in 2023
The 2023 season was a breakout for head coach Brian Daboll and the New...
By Nick Brown -
UFC
/ 2 years agoSaturday’s Fight Night Features Vettori vs. Cannonier Main Event
Namely, Marvin Vettori vs. Jared Cannonier: UFC Vegas 75 will happen this weekend. Indeed, middleweights...
By Nick Brown -
MLB
/ 2 years agoBrewers Host Pirates in Friday Apple TV NL Central Battle for First
At the beginning of the season, the Milwaukee Brewers were the MLB betting favorite...
By Nick Brown